Enhanced Weight Loss and Metabolic Benefits from Combining THRβ and GLP-1R Agonism
Time: 12:30 pm
day: Conference Day One
Details:
- Exploring thyroid hormone receptor-beta (THRβ) agonist in combination with GLP-1R
- Examining the prevention of the metabolic adaptation that typically reduces energy expenditure during weight loss, resulting in greater overall weight loss and preservation of lean mass
- Detailing the preclinical findings that combination of TERN-501 plus GLP-1R agonism led to greater weight loss and increased fat mass reduction compared to GLP-1R agonism alone, highlighting its potential as a synergistic partner for muscle-preserving weight reduction therapies
