Preclinical Development of Oral Small Molecule GLP-1 Agonists: Challenges & Solutions
Time: 12:00 pm
day: Day Two
Details:
- Screening paradigms for in vitro cell efficacy, ADME and DMPK
- Validating appropriate in vivo pharmacodynamic models
- In vivo efficacy and safety assessments: early and often
- Clinical Candidate nomination: data from Ambrosia’s proprietary program to be presented