PRE-CONFERENCE WORKSHOP DAY
Tuesday 10 December, 2024
9:00 am Registration & Morning Coffee
WORKSHOP A
9:30 am Obesity Heterogeneity: Deep Diving into Molecular Mechanisms Driving Heterogeneity Across the Population for Segmentation for a Personalized Treatment Approach
Synopsis
This discussion led workshop delves into the intricate molecular mechanisms driving obesity heterogeneity, paving the way for a personalized treatment approach. Explore ground-breaking strategies and methodologies that push the boundaries of our understanding of obesity, uncovering unprecedented insights into the diverse factors
influencing weight management across different populations.
Highlights include:
- Implementing back translation of human data from the abundance of clinical data to critically examine responders vs non-responders
- Exploring the science behind GLP non-responders and those with low percentage weight loss to
- Key considerations for tackling obesity in the elderly and the significant risk of muscle loss compared to the standard population
- Uncover the differential considerations for the treatment and management of paediatric obesity
- Examine the Gut-Brain axis to better understand the heterogeneity of tolerability and gastrointestinal symptoms
12:30 pm Lunch Break & Networking
WORKSHOP B
1:30 pm Exploring Muscle Dynamics in Obesity: From Muscle Loss to Therapeutic Opportunities
Synopsis
This interactive workshop will explore the critical relationship between muscle health and obesity, with a focus on understanding and mitigating muscle loss in obese populations. Delve into the unique challenges posed by sarcopenia in obesity and uncover therapeutic strategies aimed at preserving muscle mass while optimizing fat loss.
This workshop will gather experts to discuss:
- Explore the dual challenge of managing obesity in populations already facing muscle deterioration, and identify potential therapeutic strategies to combat sarcopenic obesity
- Delve into the consequences of rapid weight loss on muscle mass and function, and discuss strategies to minimize muscle degradation while optimizing fat loss
- Evaluate the effects of GLP-1 receptor agonists on skeletal muscle, and discuss how these insights can guide the design of more comprehensive obesity treatments
- Review cutting-edge research on manipulating skeletal muscle during weight loss to enhance overall metabolic health and prevent the onset of sarcopenia in obese patients
- Investigate the role of animal models in elucidating the complex relationship between muscle and fat tissues, and how these models inform therapeutic development